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This abstract is assigned to session AOB Free Papers 1

Presentation type	Oral presentation
Title	Radiation Retinopathy in patients with Ruthenium brachytherapy for uveal melanoma

Purpose	Radiation retinopathy is a major cause of vision loss following brachytherapy for uveal melanoma. Despite various proposed classifications for assessing radiation retinopathy, there is no universally accepted score system in clinical pratice. This study aims to develop a multimodal classification system for radiation retinopathy, to determine its incidence and characterise clinical outcomes
Methods	Retrospective cohort study. Associations with radiation retinopathy severity, visual acuitiy and macular thickness were analysed.
Results	121 patients were included, of whom 59 developed radiation retinopathy in some form (49%) during follow-up. A classification system for radiation retinopathy was developed based on fundus phtografhy and optical coherence tomograhy. Increasing grades of radiation retinopathy were associated with poorer vision, and increases macular thickness.
Conclusion	Although radiation retinopathy does nog appear to impact on survival, its severity is strongly associated with visual outcomes. The proposed classification system porvides a clinically useful framework for standardised evaluation and risk stratification.
Conflict of interest	No

Authors 1

Last name	MISSOTTEN
Initials	G
Department	Universitaire ziekenhuizen Leuven
City	Leuven

Authors 2

Last name	Wassouf
Initials	M.
Department	Universitaire ziekenhuizen Leuven
City	Leuven

Authors 3

Last name	Christiaens
Initials	M.
Department	Universitaire ziekenhuizen Leuven, dienst radiotherapie
City	Leuven

Authors 4

Last name	De Clerck
Initials	I
Department	Universitaire ziekenhuizen Leuven
City	Leuven

Authors 5

Last name	Van Calster
Initials	J
Department	Universitaire ziekenhuizen Leuven
City	Leuven