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Presentation type	Oral presentation
Title	Driving Forces and Perceived Barriers for the Adoption of Novel Endothelial Cell Therapies: An International Survey of Corneal Surgeons

Purpose	To evaluate corneal transplant surgeons’ current practice pattern and their interest and adoption attitudes toward novel endothelial cell replacement via an online survey.
Methods	The online survey contained 25 questions (13 single-choice, 12 multi-choice) separated in the 4 sections “General Demographics and Practice Patterns,” “New Corneal Endothelial Cell Replacement Therapies,” “Perceived Barriers,” and “Surgeon Perspectives on Graft Design for Tissue-Engineered Endothelial Grafts.” A total of 116 responses were evaluated.
Results	Most respondents (97.4%, n = 113) would consider the adoption of novel, commercially available cell replacement therapies in the future. Ease of surgical handling, better clinical outcomes, and donor tissue shortages were seen as the main driving forces for adoption. Although being acknowledged as an easier procedure, most respondents expressed that cell injection should be restricted to corneal specialists and not be performed by comprehensive ophthalmologists.
Conclusion	The survey shows a positive attitude for adopting new endothelial cell replacement therapies among corneal surgeons. Perceived barriers and expected training requirements for the clinical adoption of the new therapies were identified and should be addressed to ensure a successful clinical translation.
Conflict of interest	No

Authors 1

Last name	LUAN
Initials	Y
Department	Vrije Universiteit Brussel (VUB),Universitair Ziekenhuis Brussel (UZB)
City	Brussels

Authors 2

Last name	Ní Dhubhghaill
Initials	S
Department	Department of Ophthalmology, UZ Brussel / Vrije Universiteit Brussel (VUB)
City	Brussels

Authors 3

Last name	Rose-Nussbaumer
Initials	J
Department	Byers Eye Institute, Department of Ophthalmology, Stanford University
City	Palo Alto

Authors 4

Last name	de Kort
Initials	C
Department	Netherlands Institute for Innovative Ocular Surgery
City	Rotterdam

Authors 5

Last name	Romano
Initials	V
Department	Eye Unit, University of Brescia
City	Brescia

Authors 6

Last name	Oellerich
Initials	S
Department	Department of Ophthalmology, UZ Brussel / Vrije Universiteit Brussel (VUB)
City	Brussels