| Presentation type | Oral presentation |
| Title | The combination of a narrowed and extended partial depth-of-field intraocular lens (COMEDI) in bilateral cataract surgery |
| Purpose | To compare visual, functional, optical, and patient-reported outcomes of bilateral narrowed partial depth-of-field (DOFi) intraocular lenses (IOLs) with a combined narrowed–extended partial DOFi strategy. |
| Methods | Patients undergoing bilateral cataract surgery were randomized to bilateral narrowed partial DOFi IOLs (mono-group) or a narrowed partial DOFi IOL in one eye and an extended partial DOFi IOL in the fellow eye (combi-group). The primary outcome was binocular distance-corrected intermediate visual acuity (DCIVA) at 66 cm 3 months postoperatively. Secondary outcomes included reading speed, contrast sensitivity, straylight, aberrometry, spectacle independence and patient satisfaction. |
| Results | Fifty patients were enrolled, with 44 completing 3-month follow-up; recruitment ended early following a planned interim analysis. Binocular DCIVA was comparable between groups (0.18 ± 0.02 vs 0.16 ± 0.02 logMAR; p = 0.45). Reading speed was significantly faster in the combi group at 1.6, 1.25, and 1.0 m print sizes (p = 0.03, 0.04, and 0.04; 95% CI 1.1–44.3, 0.5–43.7, and 2.1–45.3, respectively). Contrast sensitivity and straylight were comparable. Internal and total-eye coma, trefoil, and total higher-order aberrations were greater in the combi group. Patient satisfaction was higher in the combi group (4.05/5 ± 0.20 vs 3.61/5 ± 0.15; p = 0.04; 95% CI 0.03–0.86). |
| Conclusion | The combined narrowed–extended partial DOFi strategy provided comparable visual acuity with superior reading performance and greater patient satisfaction, without compromising contrast sensitivity or straylight. |
| Conflict of interest | No |
| Last name | VAN SCHOOR |
| Initials | R |
| Department | Vrije Universiteit Brussel |
| City | Brussel |
| Last name | Termote |
| Initials | K |
| Department | Vrije Universiteit Brussel |
| City | Brussel |