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Presentation typeE-poster
TitleMycoplasma-induced Rash and Mucositis (MIRM): New Kid on the Block?
PurposeTo present a case series of 3 pediatric patients (aged 8, 12, and 16 years) diagnosed with MIRM, focusing on the ocular manifestations, clinical course, management, and outcome.
MethodsA case series of 3 pediatric patients.
ResultsAll 3 patients presented with cutaneous involvement and severe mucositis. Serologic testing confirmed Mycoplasma pneumoniae infection. Ocular involvement was characterized by acute pseudomembranous conjunctivitis and severe conjunctival ulceration. Patient 1 also reported ocular pain and temporary vision loss. Conjunctival pseudomembranes were consistently debrided and all patients were treated with a combination of systemic antibiotics, topical corticosteroids and antibiotics, and extensive lubrication. In patients 1 & 2, heparin-containing artificial tears were used as a fibrinolytic agent to aid in the resolution of pseudomembranes. During follow up pseudomembranes resolved, conjunctival erosions healed without residual scarring, and none of the patients developed symblepharon or experienced long-term visual impairment.
ConclusionAlthough MIRM shares clinical features with Stevens-Johnson Syndrome (SJS) and erythema multiforme (EEM), this case series highlights the importance of recognizing MIRM as a distinct clinical entity. MIRM typically presents with milder ocular and systemic manifestations and has a better outcome. The use of heparin-containing artificial tears may provide additional benefit in managing MIRM-associated pseudomembranous conjunctivitis, although further research is needed to confirm this hypothesis.
Conflict of interestNo
Authors 1
Last nameMOURISSE
InitialsS
DepartmentDpt of Ophthalmology, Ghent University Hospital
CityGhent
Authors 2
Last nameRoels
InitialsD
DepartmentDpt of Ophthalmology, Ghent University Hospital
CityGhent
Authors 3
Last nameWillekens
InitialsJ
DepartmentDpt of Pediatrics, Ghent University Hospital
CityGhent
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