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Presentation type	E-poster
Title	OCT-A "normative-value" range in healthy subjects

Purpose	To attempt to establish a normative-value range for OCTA in healthy subjects. OCTA is a relatively new diagnostic tool that reflects the vascular density of the optic disc and macula, both of which are important in the development of glaucoma. It also shows complete choriocapillaris loss in areas of localized peripapillary atrophy, the so-called deep microvascular dropout. OCTA values are biased and influenced by several systemic diseases and even by the quality and segmentation of the layers. With this study, we rather wanted to observe if there were physiological changes in vessel density by ageing and to guestimate a normative value.
Methods	73 healthy subjects were examined. The patients had no known or previous abnormal IOP >21 mmHg and the aspect of the optic disc was normal with a healthy neuroretinal rim. OCT and OCTA images were captured by Solix Optovue. The en-face superficial, en-face deep and en-face choroid layers were examined. Vascular density was measured in the macula 6x6 mm and the peripapillary sector, 4.5x4.5 mm of the optic disc. Foveal avascular zone and the vessel density around it were measured as well. All the images with a quality score of <6 or a SSI<48 and all the images with an abnormality of the retina or disc were discarded from the calculation.
Results	Vascular density in macula decreased with age, this decline was more important after the 5th decade. The avascular zone became larger with age and its vascular density less important. Other parameters seem to be stable in our study.
Conclusion	This study provides important data: a range of OCTA parameters for each decade, which can help distinguish neurodegenerative disease progression from normal physiological changes.
Conflict of interest	No

Authors 1

Last name	ABDOULI
Initials	N
Department	Cliniques Universitaires Saint-Luc
City	Bruxelles

Authors 2

Last name	VAUCOURT
Initials	T

Authors 3

Last name	GOUVERNEUR
Initials	F

Authors 4

Last name	EL MAFTOUHI
Initials	A

Authors 5

Last name	POURJAVAN
Initials	S
Department	Cliniques Universitaires Saint-Luc
City	Bruxelles