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Presentation type	E-poster
Title	Optical Coherence Tomography angiography volume measurements of the posterior pole of the eye in children under myopia control treatment. The effect of one-month daily atropine 0.1% eye drop use.

Purpose	In atropine 0.1% myopia prevention we noted a rapid decrease in axial length (AxL). The purpose of this study was to investigate the cause and thus better understand atropine’s mechanism of action. The present study investigates, whether atropine’s effect on the AxL comes forth from an increase in choroidal thickness (ChT) using SS-OCTa (swept source optical coherence tomography angiography).
Methods	Twenty-five myopic children (25 eyes) (9 male and 16 females; mean age 11.8 years, range 7-15 years) were enrolled. Using SS-OCTa, ChT and CSV (choroidal stromal volume) were measured at baseline and at 1 month. AxL measurements were made on the same days.
Results	After one month of daily atropine 0.1% instillation in the subjects, ChT increased by 22.41 ± 4.20 μm (p < 0,01), CSV increased by 1.08 ± 1.02 mm3 (p < 0,01) and AxL decreased by 0.044 ± 0.016 mm (p < 0,05), shown by mean ± standard error (SE). The CSV and ChT increase show a negative correlation with the AxL decrease of -0.462 and -0.374 respectively, demonstrating a weak to moderate correlation.
Conclusion	Administration of atropine 0.1% eye drops daily over one month demonstrated a decrease in AxL concurrent with an increase in ChT and CSV. A direct cause-effect between these two parameters is plausible.
Conflict of interest	No

Authors 1

Last name	KOULALIS
Initials	J
Department	UZ Brussel
City	Jette

Authors 2

Last name	NELIS
Initials	P
Department	Augenklinik Berlin-Buch, Helios Klinikum Berlin-Buch
City	Berlin

Authors 3

Last name	COOLS
Initials	W
Department	Core facility - Support for Quantitative and Qualitative Research (SQUARE), Vrije Universiteit Bruss
City	Brussel

Authors 4

Last name	TEZCAN
Initials	F
Department	UZ Brussel
City	Jette

Authors 5

Last name	KUIJPERS
Initials	R
Department	UZ Brussel, Albert Schweitzer Hospital, Erasmus Universiteit Rotterdam
City	UZ Brussel, Dordrecht, Rotterdam