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Title

Primary vitreous cysts: two case reports

Purpose	To report two cases of primary vitreous cysts with discussion of their pathophysiology and management.
Methods	Clinical examination with fundus photography, ultrasound and optical coherence tomography. Histopathology was performed in the first case.
Results	The first case illustrates a pigmented, free-floating cyst, which was removed during a 27g vitrectomy. Histopathology shows a single layer of pigmented epithelium and confirms the previously reported presence of a PAS-positive basement membrane. The second case shows a sessile, non-pigmented cyst associated with significant anisometropia.
Conclusion	Primary vitreous cysts are rare and can have a wide range in their clinical aspect. This likely reflects whether they originate either from the pigment epithelium or the primary hyaloidal system. Management of vitreous cysts is mostly conservative, but pars plana vitrectomy can be used safely, if the symptoms are debilitating.
Conflict of interest	No

Authors 1

Last name	ROBBEN
Initials	P
Department	UZ Leuven
City	Leuven

Authors 2

Last name	Van Ginderdeuren
Initials	R
Department	UZ Leuven
City	Leuven

Authors 3

Last name	Thoma
Initials	D
Department	UZ Leuven
City	Leuven

Authors 4

Last name	Dehislage
Initials	C
Department	Ziekenhuis Oost Limburg
City	Genk

Authors 5

Last name	Van Calster
Initials	J
Department	UZ Leuven
City	Leuven

Authors 6

Last name	Blanckaert
Initials	J
Department	Jan Yerman ziekenhuis
City	Ieper

Authors 7

Last name	Casteels
Initials	I
Department	UZ Leuven
City	Leuven