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This abstract is assigned to session AOB Poster session 1 - Glaucoma – Posterior segment/Retinal disease

Title	Acute frosted retinal periphlebitis in a patient with Mediterranean fever
Abstract Nr.	1026

Purpose	To present a case of frosted branch periphlebitis in a patient with familial Mediterranean fever (FMF).
Methods	Case report.
Results	A 37-year-old male presented with a decreased visual acuity (VA) and floaters for 4 days on the LE. VA was 20/20 RE and 20/28 LE. Anterior segment and fundus examinations of the RE were normal. Slit lamp examination of LE revealed a mild non-granulomatous anterior uveitis and vitritis. Intraocular pressure was 19 mmHg RE and 12 mmHg LE. Fundoscopy of the LE showed typical appearance of frosted branch periphlebitis with perivascular sheathing of the retinal veins and scattered retinal haemorrhages. Fluorescein angiography of the LE showed optic disc and segmented vascular staining without macular leakage. Ocular coherence tomography of the LE demonstrated a macular thickening and few intraretinal cysts. The ophthalmological history was negative. The general history and work up were significant for FMF and a positive lupus anticoagulant. One week later, the fundus findings worsened with a severe decrease of VA of the LE to 20/200. A single intravitreal injection of bevacizumab (BV) was performed. Three weeks after injection, fundus findings progressively improved with a decrease of the macular thickening and an improvement of the VA to 20/25. Clinical improvement continued up to the last visit (19 weeks after the injection) with a VA that reached back 20/20 with no signs of active inflammation.
Conclusion	This case demonstrates a possible association between unilateral frosted branch periphlebitis and FMF.
Conflict of interest	No

Authors 1

Last name	KÖSE
Initials	Ö
Department	CHU St-Pierre, CHU Brugmann
City	Brussels

Authors 2

Last name	WILLERMAIN
Initials	F
Department	CHU St-Pierre, CHU Brugmann
City	Brussels

Authors 3

Last name	EL OUARDIGHI
Initials	H
Department	CHU St-Pierre
City	Brussels

Authors 4

Last name	GUILLAUME
Initials	MP
Department	CHU St-Pierre
City	Brussels

Authors 5

Last name	CASPERS
Initials	L
Department	CHU St-Pierre
City	Brussels

Authors 6

Last name	POSTELMANS
Initials	L
Department	CHU Brugmann
City	Brussels

Authors 7

Last name	MAKHOUL
Initials	D
Department	CHU St-Pierre, CHU Brugmann
City	Brussels