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This abstract is assigned to session AOB: Academia Ophthalmologica Belgica

Title	A Retrospective Cohort Study in Patients with Tractional Diseases of the Vitreomacular Interface (ReCoVit)
Abstract Nr.	1024

Purpose	To extract real-world data on tractional diseases on the spontaneous evolution of the vitreomacular interface (VMI): vitreomacular adhesion (VMA), vitreomacular traction (VMT) and macular hole (MH).
Methods	556 patients who presented with optical coherence tomography (OCT) findings related to tractional diseases of the VMI (187 with bilateral disease) between 2009 and 2013 were included. Median follow-up was 25.4 months. Kaplan-Meier analysis, non-parametric tests, Wilcoxon matched-pairs signed-ranks tests, and logistic regression models were all used.
Results	Vision loss and metamorphopsia were the leading causes for referral. Spontaneous resolution occurred in 46/203 eyes with VMT (22.7%) and in 9/124 eyes with VMA (7.3%; (P<.001). In the former group, 14 eyes had improved VA (34.1%; P=.001). During follow-up, 14/124 VMA eyes had disease progression (11.3%); 6 progressed to MH (4.8%). Eleven of the 203 VMT eyes progressed to MH (5.4%); 52 of the 203 VMT eyes that had disease progression warranted vitrectomy (25.6%). Of the VMA eyes, 6/124 had disease progression warranting vitrectomy (4.8%). There were 47/53 MH with VMT eyes that underwent vitrectomy (88.7%), and 152/176 MH without VMT eyes that underwent PPV (86.4%). Visual acuity outcome was determined in the VMT group by comparing baseline to last measurement in the follow-up in three subgroups: spontaneous release, no release and vitrectomy. The spontaneous release subgroup showed the best outcome.
Conclusion	Limited clinical benefit is achieved by watchful waiting. Spontaneous resolution of VMT and VMA is rare, while disease progression requiring vitrectomy was more common. Better VA outcomes were found in eyes with spontaneous resolution compared to the other groups.

Authors 1

Last name	STALMANS
Initials	P
Department	Dept Ophthalmology UZLeuven
City	Leuven