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Title	Correlation between peripapillary choroidal thickness and retinal vessel oxygen saturation in young healthy individuals
Abstract Nr.	1047

Purpose	To investigate the correlation between the peripapillary choroidal thickness (CT) and the retinal vessel oxygen saturation (SO2) in young healthy individuals.
Methods	Young healthy volunteers were recruited in this observational, cross-sectional study. Peripapillary CT was obtained using enhanced depth imaging optical coherence tomography (EDI-OCT). Arterial (SaO2) and venous retinal oxygen saturation (SvO2) were measured by a noninvasive spectrophotometric retinal oximeter in all four quadrants. Spearman’s rank correlation and multiple regression analysis were used to determine relationships between choroidal thickness and oxymetric parameters.
Results	54 eyes of 54 individuals aged 21.6±1.1 years were analyzed. Average SaO2 (92.3±3.0%) and SvO2 (55.4±4.6%) were positively correlated with the average peripapillary CT at 500µm from the optic disc margin (Spearmans’s R = 0.477 , p < 0.001 and 0.414 , p < 0.002 respectively). These results were confirmed to be independent of intraocular pressure and hemodynamic parameters on multivariate linear regression analysis (p < 0.01).
Conclusion	In young healthy individuals, retinal vessel oxygen saturation appears to be positively correlated with the peripapillary choroidal thickness.

Authors 1

Last name	VAN KEER
Initials	K
Department	Department of Ophthalmology, University Hospitals Leuven
City	Leuven

Authors 2

Last name	ABEGãO PINTO
Initials	L
Department	Department of Pharmacology and Neurosciences, Faculty of Medicine of Lisbon
City	Lisbon

Authors 3

Last name	WILLEKENS
Initials	K
Department	Department of Ophthalmology, University Hospitals Leuven
City	Leuven

Authors 4

Last name	STALMANS
Initials	I
Department	Department of Ophthalmology, University Hospitals Leuven
City	Leuven

Authors 5

Last name	VANDEWALLE
Initials	E
Department	Department of Ophthalmology, University Hospitals Leuven
City	Leuven