Title | Long-term results of low-fluence photodynamic therapy in chronic central serous chorioretinopahy |
Purpose | To evaluate long-term results of low-fluence photodynamic therapy (PDT) with verteporfin in the treatment of Chronic Central Serous Chorioretinopathy (CCSC). |
Methods | Retrospective medical record review of 42 eyes (39 patients) who received low-fluence PDT for the treatment of CCSC. Visual acuity, fundus biomicroscopy, fluorescein angiography (FA), indocyanine green angiography (ICG) and optical coherence tomography (OCT) were analysed. |
Results | Forty two eyes (39 patients) with CCSC received low fluence PDT. Mean follow-up after PDT was longer than 3 years (39,43 months; range, 12-96 months; median, 36 months). Mean logMar best corrected visual acuity (BCVA) improved significantly from 0,32 (0,48 Snellen visual acuity) to 0,1 (0,80 Snellen visual acuity) at the last follow up which corresponds to a gain of 2,2 lines in logMar scale. Complete resolution of central subretinal fluid on OCT was achieved 6 months after 1 PDT in 41 eyes and after 2 PDTs in 1 eye (treated at 3 months after first PDT). No treatment-related side effects were observed. |
Conclusion | Low fluence PDT for CCSC is efficient and safe at long term. |
Last name | LEYS |
Initials | E |
Department | CHU Brugmann - CHU Saint-Pierre |
City | Brussels |
Last name | TUTTLE |
Initials | S |
Department | CHU Brugmann |
City | Brussels |
Last name | RASQUIN |
Initials | F |
Department | Erasme |
City | Brussels |
Last name | NEU |
Initials | F |
Department | Erasme |
City | Brussels |
Last name | POSTELMANS |
Initials | L |
Department | CHU Brugmann |
City | Brussels |