THE BELGIAN OPHTHALMIC ASSOCIATIONS
View abstract
Cet abstract a été assigné à session AOB Free Papers 1
| Type de présentation | Oral presentation |
| Titre | Minimally Invasive Bleb Surgery (MIBS) in Patients at High Risk of Trabeculectomy Failure: A Scoping Review |
| But | Trabeculectomy remains the reference filtration procedure, but fails more often in eyes with previous ocular surgery, secondary glaucoma, black race, long-term topical antiglaucoma therapy or young age. This scoping review maps the evidence on minimally invasive bleb surgery (MIBS) in patients with open-angle glaucoma carrying at least one of these recognised predictors of trabeculectomy failure. |
| Méthodes | Conducted in accordance with PRISMA-ScR guidelines. MEDLINE (via PubMed), Embase and Web of Science were searched for human studies in English, with no date restriction. The primary outcome was intraocular pressure (IOP); secondary outcomes were IOP-lowering medication use, treatment success, additional interventions and hypotony. |
| Résultats | Thirty-six studies (2017-2026, up to 1,379 eyes) were included: 30 retrospective, 6 prospective, no randomised trials. Median cohort: 24.5 eyes (range 5-153). Median IOP fell from 25.1 to 13.7 mmHg (median relative reduction 42.2%), and median medication count from 3.5 to 0.7 (median reduction 79.0%). Median reported rates: needling 33.8% (28 studies), bleb revision 19.8% (22 studies), reoperation 13.0% (28 studies), hypotony 15.6% (reported by only half the studies). Success definitions varied widely across studies. |
| Conclusion | In eyes at high risk of trabeculectomy failure, MIBS was consistently followed by lower IOP and medication burden, alongside a substantial reintervention burden. Comparison with trabeculectomy or glaucoma drainage devices remains unmade; prospective comparative studies are needed. |
| Conflit d'intérêt | Non |
| Détails conflits d'intérêt | None relevant |
Auteurs 1
| Nom | DEMEESTERE |
| Initiales | D |
| Institut | UZ/KU Leuven |
| Ville | Leuven |
Auteurs 2
| Nom | Jacobs |
| Initiales | T |
| Institut | UZ/KU Leuven; CERA |
| Ville | Leuven; Melbourne |
Auteurs 3
| Nom | Martin |
| Initiales | KR |
| Institut | CERA |
| Ville | Melbourne |
Auteurs 4
| Nom | Kerr |
| Initiales | NM |
| Institut | CERA |
| Ville | Melbourne |
Auteurs 5
| Nom | Van Eijgen |
| Initiales | J |
| Institut | UZ/KU Leuven |
| Ville | Leuven |
Auteurs 6
| Nom | Stalmans |
| Initiales | I |
| Institut | UZ/KU Leuven |
| Ville | Leuven |