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Type de présentation	Oral presentation
Titre	The importance of fluo-angiographic evaluation of retinopathy of prematurity

But	Peripheral avascular retina (PAR) might develop after anti-VEGF therapy for ROP, which could lead to secondary retinal complications. Fluo-angiography (FA) is the best way to visualize PAR, however scarce research is available due to the more invasive nature of the procedure. Three children with different ROP stages and treatment were examined with FA.
Méthodes	Fundus photography (FP) and FA were performed with 7,7 mg/kg dosage before peripheral argon laser photocoagulation (ALP) under general anaesthesia.
Résultats	Patient 1: Gestational age (GA) 26 weeks + 1 day: aflibercept (afl) 0,01 ml was administered in left eye (OS) at postmenstrual age (PMA) 40 weeks + 6 days. ALP OS at 24 months PMA. FA: no significant differences between the eyes, no PAR was noticeable. However, the branching of the vessels of the treated eye was more abnormal. Peripheral vascular branches showed a perpendicular configuration instead of the normally more linear growth of the vessels. Patient 2: GA 24 weeks + 1 days: afl 0.025mL bilateral at PMA 34 weeks + 2 days. ALP at 45 months PMA. FP: temporally a clear ridge with avascular zones of more than 2 disc diameters, which accorded to the FA images. Active leakage at the point of the ridge in OS was imaged. Patient 3: GA 26 weeks + 5 days , ALP at 41 weeks + 2 days PMA. FA: PAR was clearly visualized. The dense activity of the temporal ridge depicted that the ROP was more advanced than could be expected by FP alone.
Conclusion	These 3 cases visualize the possible differences in peripheral vasculature and PAR in 3 different treatment strategies for ROP and reveal the importance of supplemental FA in the assessment of ROP.
Conflit d'intérêt	Non

Auteurs 1

Nom	PULYAVINA
Initiales	A
Institut	Antwerp University Hospital (UZA)
Ville	Antwerp

Auteurs 2

Nom	Van Severen
Initiales	V
Institut	UZA
Ville	Antwerp

Auteurs 3

Nom	van Zeeburg
Initiales	EJT
Institut	UZA and University of Antwerp
Ville	Antwerp