Type de présentation | E-poster |
Titre | Treatment of Metastatic Uveal Melanoma |
But | Description of the various treatments and follow-up of metastatic uveal melanoma patients. Assesment whether the introduction of immune checkpoint inhibitors improved survival. |
Méthodes | retrospective single-center study. |
Résultats | 121 metastatic uveal melanoma patients were registered. No significant improvement of the survival could be established after the introduction of immune checkpoint inhibitors. Only liver-directed and local oligometastatic approaches were associated with a lower chance of mortality when compared tot immune checkpoint inhibitors (p=0.0025). |
Conclusion | Although we documented responses tot immune checkpoint inhibitors, our analyses do not demonstrate an overall survival improvement of checkpoint inhibitors over alternative treatment strategies. However, local treatment options, whether liver-directed or for oligometastatic disease, may be beneficial and should be considerd. |
Conflit d'intérêt | Non |
Nom | MISSOTTEN |
Initiales | G |
Institut | Jessa Oogkliniek Hasselt and University Hospitals Leuven |
Ville | Hasselt/Leuven |
Nom | Vanaken |
Initiales | L |
Institut | Department of Oncology, University Hospitals Leuven |
Ville | Leuven |
Nom | Van Ginderdeuren |
Initiales | R |
Institut | Department of ophthalmology, University Hospitals Leuven |
Ville | Leuven |
Nom | Thal |
Initiales | D |
Institut | Department of Pathology, University Hospitals Leuven |
Ville | Leuven |
Nom | Bechter |
Initiales | O |
Institut | Department of Oncology, University Hospitals Leuven |
Ville | Leuven |
Nom | Clement |
Initiales | P |
Institut | Department of Oncology, University Hospitals Leuven |
Ville | Leuven |