| Type de présentation | E-poster |
| Titre | Treatment of Metastatic Uveal Melanoma |
| But | Description of the various treatments and follow-up of metastatic uveal melanoma patients. Assesment whether the introduction of immune checkpoint inhibitors improved survival. |
| Méthodes | retrospective single-center study. |
| Résultats | 121 metastatic uveal melanoma patients were registered. No significant improvement of the survival could be established after the introduction of immune checkpoint inhibitors. Only liver-directed and local oligometastatic approaches were associated with a lower chance of mortality when compared tot immune checkpoint inhibitors (p=0.0025). |
| Conclusion | Although we documented responses tot immune checkpoint inhibitors, our analyses do not demonstrate an overall survival improvement of checkpoint inhibitors over alternative treatment strategies. However, local treatment options, whether liver-directed or for oligometastatic disease, may be beneficial and should be considerd. |
| Conflit d'intérêt | Non |
| Nom | MISSOTTEN |
| Initiales | G |
| Institut | Jessa Oogkliniek Hasselt and University Hospitals Leuven |
| Ville | Hasselt/Leuven |
| Nom | Vanaken |
| Initiales | L |
| Institut | Department of Oncology, University Hospitals Leuven |
| Ville | Leuven |
| Nom | Van Ginderdeuren |
| Initiales | R |
| Institut | Department of ophthalmology, University Hospitals Leuven |
| Ville | Leuven |
| Nom | Thal |
| Initiales | D |
| Institut | Department of Pathology, University Hospitals Leuven |
| Ville | Leuven |
| Nom | Bechter |
| Initiales | O |
| Institut | Department of Oncology, University Hospitals Leuven |
| Ville | Leuven |
| Nom | Clement |
| Initiales | P |
| Institut | Department of Oncology, University Hospitals Leuven |
| Ville | Leuven |