THE BELGIAN OPHTHALMIC ASSOCIATIONS
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| Type de présentation | E-poster |
| Titre | SARS-CoV-2 RNA detection in conjunctival swabs and ocular surface manifestations of patients hospitalized for COVID-19 pneumonia: a Belgian cohort. |
| But | To investigate the presence of SARS-CoV-2 in the tears of hospitalized COVID-19 patients and to assess systemic and ophthalmic clinical characteristics in a Belgian cohort |
| Méthodes | Prospective study of adult patients hospitalized for COVID-19 pneumonia confirmed by a chest computer tomography (CT) with no recent diagnosis or exacerbation of an ocular pathology. After completing an ocular symptom questionnaire, the patients underwent a macroscopic ocular exam and a conjunctival swab. A reverse transcriptase polymerase chain reaction (RT-PCR) was performed on the swabs to identify SARS-CoV-2 RNA. Clinicobiological data and PCR results of both ocular and nasopharyngeal samples were collected. |
| Résultats | Two patients of 58 (3,45%) had a positive conjunctival PCR: one with <10E3 copies/ml, the second highly positive with >=10E3 - <10E5 copies/ml. None of them had ocular symptoms. 13 patients (22%) presented ocular symptoms such as tearing (69,23%), redness (53,85%), burning 38% or itching 15,38%. Linear regression found that there was a significant statistical correlation between the presence of ocular and neurological symptoms (p= 0,021). |
| Conclusion | It is possible to find tear fluids with a high viral load but the probability of this occurrence appears to be rather low. The presence of SARS-CoV-2 in tears was however not associated with the presence of symptoms in this study. Ocular symptoms may not be related to the presence of the virus itself. |
| Conflit d'intérêt | Non |
Auteur 1
| Nom | VALYI |
| Initiales | Z |
| Institut | CHU Saint Pierre, Ophtalmologie |
| Ville | Bruxelles |
Auteur 2
| Nom | Khalil |
| Initiales | M |
| Institut | CHU Saint Pierre, Ophtalmologie |
| Ville | Bruxelles |
Auteur 3
| Nom | Van Den Wijngaert |
| Initiales | S |
| Institut | Laboratoire Hospitalier Universitaire de Bruxelles (LHUB-ULB), Microbiologie |
| Ville | Bruxelles |
Auteur 4
| Nom | Konopnicki |
| Initiales | D |
| Institut | CHU Saint Pierre, Maladies Infectieuses |
| Ville | Bruxelles |
Auteur 5
| Nom | Willermain |
| Initiales | F |
| Institut | CHU Saint Pierre, Ophtalmologie |
| Ville | Bruxelles |
Auteur 6
| Nom | Bruyneel |
| Initiales | M |
| Institut | CHU Saint Pierre, Pneumologie |
| Ville | Bruxelles |