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Type de présentation	Oral presentation
Titre	Unusual occurrence of graft-host interface epithelial ingrowth imitating infection following DMEK surgery

But	To report our experience of interface epithelial ingrowth post-Descemet membrane endothelial keratoplasty (DMEK) surgery.
Méthodes	Patient was examined, diagnosed and treated by the corneal team in the Ophthalmology Department at University Hospitals of Leicester, a tertiary care hospital.
Résultats	An 81-year-old female with Fuchs’ endothelial dystrophy, cataract and dry age-related macular degeneration underwent uncomplicated left triple DMEK surgery. Pre-operative left distance visual acuity was 0.50 LogMAR. At 7 weeks post-operatively, multiple left graft-host interface opacities were noted and suspected to be of infectious origin. An emergency anterior chamber tap was performed for microbiology culture, and intra-cameral Voriconazole and Cefuroxime were injected. The patient was started on topical levofloxacin 0.5% and voriconazole 1% hourly. Topical dexamethasone 0.1% was stopped. AS-OCT showed hyperreflective interface deposits corresponding to the opacities. Aqueous tap cultures were negative. Topical antimicrobial treatment was tapered and discontinued, and topical steroids were recommenced. The clinical diagnosis of epithelial ingrowth was made and confirmed by in vivo confocal microscopy (IVCM). Despite progression, the patient remained asymptomatic with a visual acuity of 0.28 LogMAR 15.5 months post-operative.
Conclusion	Epithelial ingrowth is a fairly unknown complication after DMEK surgery which can mimic an insidious infectious keratitis. Appropriate investigation and treatment are required, and IVCM may serve as a useful diagnostic modality in achieving the correct diagnosis.
Conflit d'intérêt	Non

Auteur 1

Nom	HOUBEN
Initiales	I
Institut	University Hospitals of Leicester NHS Trust
Ville	Leicester

Auteur 2

Nom	Dhillon
Initiales	N
Institut	University Hospitals of Leicester NHS Trust
Ville	Leicester

Auteur 3

Nom	Darren
Initiales	T
Institut	Queen's Medical Centre
Ville	Nottingham

Auteur 4

Nom	Harminder
Initiales	D
Institut	Queen's Medical Centre
Ville	Nottingham