View abstract

Cet abstract a été assigné à sessions
Type de présentationE-poster
TitreNormal tension glaucoma: a dynamic optical coherence tomography angiography study.
ButVascular dysregulation seems to play a role in the pathogenesis of glaucoma, especially normal tension glaucoma (NTG). The development of optical coherence tomography angiography (OCT-A) enabled measurement of the retinal microvasculature with high repeatability. Nonetheless, only a few studies transformed OCT-A into a dynamic exam employing a sympathomimetic stimulus. The goal of this study was to use this dynamic OCT-A exam (1) to differentiate healthy individuals from glaucoma patients and (2) to distinguish glaucoma subcategories, NTG and high-tension primary open angle glaucoma (POAG).
MéthodesRetinal vessel density (VD) in NTG patients (n=16), POAG patients (n=12) and healthy controls (n=14) was compared before and during a hand grip test with a hydraulic dynamometer.
RésultatsAt baseline, peripapillary VD was lower in POAG and NTG compared to healthy controls and slightly higher in NTG compared to POAG when corrected for mean arterial pressure (MAP). Peripapillary and macular (superficial and deep) VD differences were found for gender, age and baseline MAP. No change in VD occurred (pre/post stimulus) in any of the groups.
ConclusionRetinal VD loss in glaucoma patients was confirmed and the necessity to correct for gender, age and especially MAP was proven. Although replication in a larger population is necessitated, OCT-A might not be the most suitable method to dynamically evaluate the retinal microvasculature.
Conflit d'intérêtNon
Détails conflits d'intérêtNA
Auteur 1
NomVAN EIJGEN
InitialesJ
InstitutUZ Leuven / KU Leuven
VilleLeuven
Auteur 2
NomHeintz
InitialesA
InstitutUZ Leuven / KU Leuven
VilleLeuven
Auteur 3
NomVan der Pluijm
InitialesC
InstitutUZ Leuven / KU Leuven
VilleLeuven
Auteur 4
NomDelporte
InitialesK
InstitutKU Leuven
VilleLeuven
Auteur 5
NomDe Witte
InitialesD
InstitutKU leuven
VilleLeuven
Auteur 6
NomMolenberghs
InitialesG
InstitutKU Leuven
VilleLeuven
Auteur 7
NomBarbosa-Breda
InitialesJ
InstitutUniversity of Porto
VillePorto
Auteur 8
NomStalmans
InitialesI
InstitutUZ Leuven / KU Leuven
VilleLeuven
top ^