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TitreAnalysis of a particular kind of central serous chorioretinopathy characterised by a leopard-spot pattern aspect in transplanted patients on long-term steroid treatment
ButThe purpose of our study is to analyse the rate of appearance of a leopard-spot pattern in transplanted patients with steroid-induced central serous chorioretinopathy (CSC) and to analyze this pattern with multimodal imaging.

MéthodesWe carried out a prospective, monocentric and interventional study on patients with heart, lung or kidney transplant and who have been treated with corticosteroid for at least 3 years. Best corrected visual acuity (BCVA), color fundus photographs, fundus autofluorescence (FAF), spectral domain optical coherence tomography (SD-OCT) and a measure of subfoveal choroidal thickness were performed. If CSC was suspected, an additional fluorescein (FA) and indocyanine green angiography (ICGA) was performed.
RésultatsAmong the 53 patients included in this study, four patients were diagnosed with CSC. Three had a “classic” form of CSC and only one showed a leopard-spot pattern.
We then associated this case with three other patients who have been previously diagnosed with chronic CSC and who showed the same kind of pattern. All cases showed a peculiar leopard-spot appearance on FAF and FA. In contrast to typical CSC, these cases did not demonstrate the typical features of hyperpermeability on ICGA and had normal choroidal thickness.
ConclusionGiven the fact that the management and prognosis of CSC are totally different from those of an intra-ocular lymphoma, it is fundamental that chronic CSC is recognized as a new differential diagnosis of “leopard-spot pattern” observed on fundoscopy.
Conflit d'intérêtNon
Auteur 1
NomNEGAHBAN
InitialesN
InstitutErasme
VilleBruxelles
Auteur 2
NomVAN BOL
InitialesL
InstitutErasme
VilleBruxelles
Auteur 3
NomAMRO
InitialesM
InstitutErasme
VilleBruxelles
Auteur 4
NomRASQUIN
InitialesF
InstitutErasme
VilleBruxelles
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