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TitreMerkel Cell Carcinoma with locoregional and distant spread
Abstract Nr.3021
ButMerkel cell carcinoma (MCC) of the eyelid is a rare disease. Nonocular MCC is known to recur in 66% and to be lethal in almost 33%. In a previous study (Ophthalmology 2008; 115: 195-201), reviewing 86 patients with eyelid MCC, only 2 patients died of distant metastasis of eyelid MCC. Here, we review 6 cases of the last 5 years with MCC.
MéthodesCase description and literature review.
RésultatsTwo of the 6 new cases showed locoregional spread, and one patient developed distant metastasis within two years of the primary diagnosis of eyelid MCC. We discuss the need of locoregional biopsies, in view of the larger literature.
ConclusionDistant metastases of eyelid MCC are less frequent than metastases of nonocular MCC, probably due to early diagnosis. Eyelid MCC larger than 2 cm, may justify locoregional surgery/biopsy.
Conflit d'intérêtNon
Auteur 1
NomVAN AERSCHOT
InitialesJ
InstitutUZLeuven, Department of ophthalmology
VilleLeuven
Auteur 2
NomVAN GINDERDEUREN
InitialesR
InstitutUZLeuven, Department of ophthalmology
VilleLeuven
Auteur 3
NomMISSOTTEN
InitialesG
InstitutUZLeuven, Department of ophthalmology
VilleLeuven
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