Titre | Infantile orbital hemangioma treated with propranolol: 2 cases |
Abstract Nr. | 3035 |
But | We report two cases of infantile orbital hemangioma with proptosis, successfully treated with propranolol. |
Méthodes | Observational report of two cases with infantile orbital hemangioma treated with propranolol, including close pediatric and ophthalmological follow-up and imaging. |
Résultats | A six week-old girl with a history of premature birth, presented at the pediatric clinic with progressive, unilateral exophthalmos. Ophthalmological evaluation showed normal pupillary reflexes and IOP, with proptosis of the right eye, more pronounced during Valsalva-maneuver. MRI was suggestive for capillary hemangioma. Propranolol was promptly started after cardiological check-up, with a spectacular response seen by day one of treatment. A 5 month-old boy, born as triplet at 34 weeks postmenstrual age, showed a unilateral proptosis of the right eye, increasing with crying. Furthermore, there were no ophthalmological abnormalities. MRI imaging showed a massive capillary hemangioma in the right orbit. After two weeks of treatment with oral propranolol, the exophthalmos and hemangioma were completely disappeared. |
Conclusion | Propranolol seems to be a rapidly effective and safe treatment for infantile orbital hemangioma. Nevertheless, administering systemic medication to an infant with a benign condition requires careful multidisciplinary consideration and experienced follow-up, considering the risk of side effects, relapse and resistance to propranolol. |
Conflit d'intérêt | Non |
Nom | DEKLERCK |
Initiales | EJ |
Institut | Dpt of Ophthalmology, Ghent University Hospital/AZ Sint-Jan Hospital |
Ville | Ghent/Bruges |
Nom | VULSTEKE |
Initiales | C |
Institut | Dpt of Ophthalmology, AZ Delta Hospital |
Ville | Roeselare |
Nom | MATTHIJS |
Initiales | I |
Institut | Dpt of Pediatrics, AZ Delta Hospital |
Ville | Roeselare |
Nom | DELBEKE |
Initiales | P |
Institut | Dpt of Ophthalmology, Ghent University Hospital/AZ Sint-Jan Hospital |
Ville | Ghent/Bruges |