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TitreClinical trial of Ultrasonic Circular Cyclo Coagulation in patients with open angle glaucoma.
Abstract Nr.1067
ButTo evaluate the relative safety and the potential efficacy of the ultrasound circular cyclo coagulation (UC3 ) treatment in patients with open angle glaucoma.
MéthodesA miniaturized high-intensity focused ultrasound (HIFU), operating at 21 MHz, was used to insonified five eyes in 5 patients during the same session. The HIFU device comprises a ring with six piezoelectric transducers inserted in a coupling cone, made of polymer and placed in direct of the eye. The six transducers are placed at regular intervals and oriented to create six epileptic cylinders surimposed on the ciliary body. The patient inclusion criteria are male or female at least 18 years old, with moderate open-angle glaucoma refractory to medical treatment and selective laser therapy. The study comprises a complete ophthalmic examination with intra-ocular pressure (IOP) measurements before the procedure and at 4 days, 1 month and 3 months after the procedure.
RésultatsThe first preliminary results show a decrease in IOP in all five patients (-3.6 to -53.0%), from a mean preoperative value of 25.8±5.4mmHg to a mean value of 20.7±7.1mmHg at 4 days. No major complications intra- or postoperative occured. The midterm follow-up results will be discussed and illustrated by UBM iconographies during the presentation.
ConclusionUC3 is a simple method for partial coagulation of the ciliary body to reduce IOP by destroying the ciliary processes and to diminish the aqueous production. This study could help defining the optimal indications of this new method of treatment.
Auteur 1
NomCOLLIGNON
InitialesNJ
InstitutCHU Sart Tilman
VilleLiège
Auteur 2
NomChapelle
InitialesAC
InstitutCHU Sart Tilman
VilleLiège
Auteur 3
NomRemont
InitialesL
InstitutCHU Sart Tilman
VilleLiège
Auteur 4
NomDupont
InitialesG
InstitutCHU Sart Tilman
Villeliège
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