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TitreCiliochoroidal Effusion Syndrome caused by sulpha derivatives: hypothesis for pathophysiologic mechanism
Abstract Nr.1054
ButProposal for a pathophysiologic mechanism for a Ciliochoroidal Effusion Syndrome caused by sulpha derivatives
MéthodesReview of literature
RésultatsWe propose that an inflow of fluid into the ciliary body exceeds the transport capacity of fluid over the non-pigmented ciliary body epithelium, due to blockage of aquaporin assisted outflow of fluid out of the ciliary body into the posterior chamber. This disequilibrium leads to ciliary body edema leaking into the supra-ciliochoroidal space, pushing the vitreous forward. This pressure leads to anterior displacement of the lens-iris diaphragm with resulting anterior chamber shallowing, myopisation and appositional angle closure.
ConclusionOur proposal for a pathophysiologic mechanism for a Ciliochoroidal Effusion Syndrome caused by sulpha derivatives gives an explanation for observations found in this syndrome: fluid in the supra-ciliochoroidal space, anterior chamber shallowing, myopisation and appositional angle closure.
Auteur 1
NomLAMBRECHT
InitialesPL
InstitutGhent University Hospital
VilleGent
Auteur 2
NomAugustinus
InitialesBA
InstitutZNA Middelheim
VilleAntwerpen
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