Abstract bekijken

Deze abstract is toegekend aan sessie AOB Free Papers 1
Type presentatieOral presentation
TitelMinimally Invasive Bleb Surgery (MIBS) in Patients at High Risk of Trabeculectomy Failure: A Scoping Review
DoelTrabeculectomy remains the reference filtration procedure, but fails more often in eyes with previous ocular surgery, secondary glaucoma, black race, long-term topical antiglaucoma therapy or young age. This scoping review maps the evidence on minimally invasive bleb surgery (MIBS) in patients with open-angle glaucoma carrying at least one of these recognised predictors of trabeculectomy failure.
MethodesConducted in accordance with PRISMA-ScR guidelines. MEDLINE (via PubMed), Embase and Web of Science were searched for human studies in English, with no date restriction. The primary outcome was intraocular pressure (IOP); secondary outcomes were IOP-lowering medication use, treatment success, additional interventions and hypotony.
ResultatenThirty-six studies (2017-2026, up to 1,379 eyes) were included: 30 retrospective, 6 prospective, no randomised trials. Median cohort: 24.5 eyes (range 5-153). Median IOP fell from 25.1 to 13.7 mmHg (median relative reduction 42.2%), and median medication count from 3.5 to 0.7 (median reduction 79.0%). Median reported rates: needling 33.8% (28 studies), bleb revision 19.8% (22 studies), reoperation 13.0% (28 studies), hypotony 15.6% (reported by only half the studies). Success definitions varied widely across studies.
ConclusieIn eyes at high risk of trabeculectomy failure, MIBS was consistently followed by lower IOP and medication burden, alongside a substantial reintervention burden. Comparison with trabeculectomy or glaucoma drainage devices remains unmade; prospective comparative studies are needed.
BelangenverstrengelingNee
Details verstrengelde belangenNone relevant
Auteurs 1
NaamDEMEESTERE
InitialenD
InstituutUZ/KU Leuven
StadLeuven
Auteurs 2
NaamJacobs
InitialenT
InstituutUZ/KU Leuven; CERA
StadLeuven; Melbourne
Auteurs 3
NaamMartin
InitialenKR
InstituutCERA
StadMelbourne
Auteurs 4
NaamKerr
InitialenNM
InstituutCERA
StadMelbourne
Auteurs 5
NaamVan Eijgen
InitialenJ
InstituutUZ/KU Leuven
StadLeuven
Auteurs 6
NaamStalmans
InitialenI
InstituutUZ/KU Leuven
StadLeuven
top ^