Abstract bekijken

Deze abstract is toegekend aan sessie AOB Free Papers 2

Type presentatie	Oral presentation
Titel	Phototherapeutic Keratectomy as an Alternative Treatment Modality for Persistent Epithelial Defect after Alkali Chemical Injury: A Case Report

Doel	To present an alternative treatment approach for persistent and recurrent corneal epithelial instability following alkali chemical injury and to describe the clinical outcome of phototherapeutic keratectomy (PTK) after failure of multimodal conservative therapies.
Methodes	A 40-year-old man presented with a painful, red eye following alkali exposure. The inferior half of the cornea showed an epithelial defect without visible limbal ischemia, with a visual acuity (VA) of 0.25. The patient was followed for 6 months with multimodal treatments for persistent and recurrent epithelial instability. Due to insufficient response, an alternative therapeutic approach with PTK was considered.
Resultaten	After the initial presentation, 20% autologous serum eye drop, contact lens therapy, epithelial debridement, insulin eye drops, botulinum toxin, and combined autologous serum and contact lens therapy were subsequently attempted for 6 months. Despite these interventions, epithelial irregularity, low vision and pain persisted. At 6 months, VA remained ≤0.25 and the patient was unable to work. PTK was then performed. One month after PTK, the epithelium was regular, VA improved to 1.0, and the patient was able to return to work.
Conclusie	PTK may represent an effective alternative approach for persistent epithelial instability following alkali chemical injury when multimodal conservative therapies fail. The recurrent epithelial breakdown despite apparent epithelial closure suggests that impaired epithelial adhesion to Bowman’s membrane may have contributed to persistent instability. PTK may provide a more favorable substrate for epithelial adhesion and regeneration.
Belangenverstrengeling	Nee

Auteurs 1

Naam	ATALAY
Initialen	G
Instituut	Department of Ophthalmology, Antwerp University Hospital (UZA)
Stad	Antwerp

Auteurs 2

Naam	Koppen
Initialen	C
Instituut	Department of Ophthalmology, Antwerp University Hospital (UZA)
Stad	Antwerp