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Type de présentation	E-poster
Titre	Unilateral orbital mass as first presentation of eosinophilic granulomatosis with polyangiitis in a 7-year-old girl.

But	To describe a rare, pediatric case of eosinophilic granulomatosis with polyangiitis (EGPA) with isolated orbital involvement.
Méthodes	A 7-year-old girl presented with a fast-growing unilateral orbital mass.
Résultats	A 7-year-old girl was referred for preseptal cellulitis, not responding to amoxicillin. She presented with a mobile, tender superotemporal orbital mass palpable through the upper eyelid, associated with pain and restricted upgaze. Other ophthalmological parameters were normal. MRI showed an intra-orbital lesion involving the superior rectus muscle and lacrimal gland, iso-intense on T1, hyperintense on T2, with marked contrast enhancement and no diffusion restriction. Biopsy revealed dense eosinophilic infiltration with granulomas and perivascular inflammation. Serology was positive for P-antineutrophil cytoplasmic antibodies (ANCA) with elevated myeloperoxidase (MPO) supporting EGPA, an ANCA associated vasculitis. Systemic work-up showed no other inflammatory lesions. Surgical debulking followed by high-dose corticosteroids and rituximab achieved sustained clinical and biochemical remission.
Conclusion	EGPA, rare in children, is an exceptionally rare cause of pediatric orbital masses. Early biopsy and immunologic testing are essential for diagnosis, differentiation with other vasculitides and orbital tumors, and prompt treatment.
Conflit d'intérêt	Non

Auteurs 1

Initiales	P
Nom	Bonny
Institut	Dept of Oftalmology, GUH
Ville	Ghent

Auteurs 2

Initiales	R
Nom	Van Paemel
Institut	Dept of Internal Medicine and Pediatrics, GUH
Ville	Ghent

Auteurs 3

Initiales	E
Nom	Schiettecatte
Institut	Dept of Radiology, GUH
Ville	Ghent

Auteurs 4

Initiales	J
Nom	Van Dorpe
Institut	Dept of Anatomic Pathology, GUH
Ville	Ghent

Auteurs 5

Initiales	T
Nom	Renson
Institut	Dept of Internal Medicine and Pediatrics, GUH
Ville	Ghent

Auteurs 6

Initiales	E
Nom	Kreps
Institut	Dept of Oftalmology, GUH
Ville	Ghent

Auteurs 7

Initiales	V
Nom	Ninclaus
Institut	Dept of Oftalmology, GUH
Ville	Ghent