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Type presentatieE-poster
TitelOCT-A "normative-value" range in healthy subjects
DoelTo attempt to establish a normative-value range for OCTA in healthy subjects. OCTA is a relatively new diagnostic tool that reflects the vascular density of the optic disc and macula, both of which are important in the development of glaucoma. It also shows complete choriocapillaris loss in areas of localized peripapillary atrophy, the so-called deep microvascular dropout. OCTA values are biased and influenced by several systemic diseases and even by the quality and segmentation of the layers. With this study, we rather wanted to observe if there were physiological changes in vessel density by ageing and to guestimate a normative value.
Methodes73 healthy subjects were examined. The patients had no known or previous abnormal IOP >21 mmHg and the aspect of the optic disc was normal with a healthy neuroretinal rim. OCT and OCTA images were captured by Solix Optovue. The en-face superficial, en-face deep and en-face choroid layers were examined. Vascular density was measured in the macula 6x6 mm and the peripapillary sector, 4.5x4.5 mm of the optic disc. Foveal avascular zone and the vessel density around it were measured as well. All the images with a quality score of <6 or a SSI<48 and all the images with an abnormality of the retina or disc were discarded from the calculation.
ResultatenVascular density in macula decreased with age, this decline was more important after the 5th decade.
The avascular zone became larger with age and its vascular density less important. Other parameters seem to be stable in our study.
ConclusieThis study provides important data: a range of OCTA parameters for each decade, which can help distinguish neurodegenerative disease progression from normal physiological changes.
BelangenverstrengelingNee
Auteurs 1
NaamABDOULI
InitialenN
InstituutCliniques Universitaires Saint-Luc
StadBruxelles
Auteurs 2
NaamVAUCOURT
InitialenT
Auteurs 3
NaamGOUVERNEUR
InitialenF
Auteurs 4
NaamEL MAFTOUHI
InitialenA
Auteurs 5
NaamPOURJAVAN
InitialenS
InstituutCliniques Universitaires Saint-Luc
StadBruxelles
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