Type presentatie | E-poster |
Titel | Treatment of Metastatic Uveal Melanoma |
Doel | Description of the various treatments and follow-up of metastatic uveal melanoma patients. Assesment whether the introduction of immune checkpoint inhibitors improved survival. |
Methodes | retrospective single-center study. |
Resultaten | 121 metastatic uveal melanoma patients were registered. No significant improvement of the survival could be established after the introduction of immune checkpoint inhibitors. Only liver-directed and local oligometastatic approaches were associated with a lower chance of mortality when compared tot immune checkpoint inhibitors (p=0.0025). |
Conclusie | Although we documented responses tot immune checkpoint inhibitors, our analyses do not demonstrate an overall survival improvement of checkpoint inhibitors over alternative treatment strategies. However, local treatment options, whether liver-directed or for oligometastatic disease, may be beneficial and should be considerd. |
Belangenverstrengeling | Nee |
Naam | MISSOTTEN |
Initialen | G |
Instituut | Jessa Oogkliniek Hasselt and University Hospitals Leuven |
Stad | Hasselt/Leuven |
Naam | Vanaken |
Initialen | L |
Instituut | Department of Oncology, University Hospitals Leuven |
Stad | Leuven |
Naam | Van Ginderdeuren |
Initialen | R |
Instituut | Department of ophthalmology, University Hospitals Leuven |
Stad | Leuven |
Naam | Thal |
Initialen | D |
Instituut | Department of Pathology, University Hospitals Leuven |
Stad | Leuven |
Naam | Bechter |
Initialen | O |
Instituut | Department of Oncology, University Hospitals Leuven |
Stad | Leuven |
Naam | Clement |
Initialen | P |
Instituut | Department of Oncology, University Hospitals Leuven |
Stad | Leuven |