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TitelClinical impact of 18F-FDG PET CT in the work up of children with uveitis.
DoelTo evaluate the usefulness of 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET/CT) in the work up of paediatric uveitis.
MethodesWe performed a retrospective study of 12 children followed for uveitis who underwent whole body 18F-FDG PET/ultra low dose CT between 2011 and 2019.
ResultatenThe average patients’ age was 11 years. 100% of patients presented bilateral uveitis, 50% panuveitis and 92% (11/12) had choroidal involvement. 5 of the 12 (42%) patients showed abnormal 18F-FDG uptake on their 18F-FDG PET/CT, including 3 with pathognomonic images of active granulomatous diseases. A biopsy was performed in one of these patients (consistent with sarcoidosis) and in the two others with abnormal 18F-FDG uptake without pathognomonic images of granulomatous disease (one consistent with sarcoidosis, the other negative). Final uveitis diagnosis were idiopathic in 58% of the patients, ocular sarcoidosis in 17% (2/12), TINU in 16,6% (2/12) and tubercular uveitis in 8,3% (1/12).
ConclusieIn this small series, 18F-FDG PET/CT provided important information for uveitis diagnosis in approximatively 30 % (4/12) of our patients. Further studies are needed to define the exact place of 18F-FDG PET/CT and chest CT in the work-up of paediatric uveitis.
BelangenverstrengelingNee
Auteur 1
NaamEL MOUDEN
InitialenJ
InstituutOphthalmology - CHU St-Pierre and CHU Brugmann - ULB
StadBruxelles
Auteur 2
NaamBazewicz
InitialenM
InstituutOphthalmology - CHU St-Pierre and CHU Brugmann - ULB
StadBruxelles
Auteur 3
NaamMakhoul
InitialenD
InstituutOphthalmology - CHU St-Pierre and CHU Brugmann - ULB
StadBruxelles
Auteur 4
NaamGoffin
InitialenL
InstituutPediatric Immuno-Rheumatology - CHU HUDERF - ULB
StadBruxelles
Auteur 5
NaamJudice
InitialenL
InstituutOphthalmology - CHU St-Pierre and CHU Brugmann - ULB
StadBruxelles
Auteur 6
NaamCaspers
InitialenL
InstituutOphthalmology - CHU St-Pierre - ULB
StadBruxelles
Auteur 7
NaamDraganova
InitialenD
InstituutOphthalmology - CHU St-Pierre and CHU Brugmann - ULB
StadBruxelles
Auteur 8
NaamGarcia
InitialenC
InstituutNuclear Medicine - CHU St-Pierre - ULB
StadBruxelles
Auteur 9
NaamWillermain
InitialenF
InstituutOphthalmology - CHU St-Pierre and CHU Brugmann - ULB
StadBruxelles
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