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TitelClinical characteristics and complications in intermediate uveitis: analysis of 15-years experience in a tertiary center for uveitis in Belgium
DoelTo report the clinical characteristics and complications of intermediate uveitis (IU) in 83 patients in a tertiary referral center for uveitis in Belgium.
Methodesa retrospective cohort study of patients with IU attending the University Hospital of Ghent from 2002 till 2018.
Resultaten83 patients(152 eyes, 55,2% females) were included. Mean age at presentation was 27y. Mean follow-up was 103 months. The most common form was idiopathic(n=50), followed by pars planitis(n=13), multiple sclerosis(MS)(n=10), sarcoidosis(n=4), Lyme disease(n=3), tuberculosis-associated uveitis(n=2) and syphilis(n=1).
Epiretinal membrane(ERM)(61,4%), cystoid macular edema(CME)(49,4%), cataract(30,1%), secondary glaucoma(13,2%) and retinoschisis(12%) were the most prevalent complications. CME and glaucoma were most sight-threatening. Main treatment indications were CME or severe vitreous inflammation. Treatment included local and systemic steroids, immunosuppressive agents and biologics next to antibiotics in infectious uveitis. Systemic treatment was indicated in case of visual acuity drop ≥ 2 lines and/or CME. More than half of the patients(n=55) received systemic treatment according to the Belgian Guidelines.
ConclusieIn our Belgian tertiary center IU was mostly idiopathic, followed by pars planitis and MS. With regard to our complications, systemic treatment was indicated in more than half of the patients proving that IU needs a strict follow-up and rarely achieves prolonged remission.
BelangenverstrengelingNee
Auteur 1
NaamTACK
InitialenM
InstituutGhent Unversity Hospital
StadGent
Auteur 2
NaamVANCLOOSTER
InitialenA
InstituutGhent University Hospital
StadGent
Auteur 3
NaamSYS
InitialenC
InstituutGhent University Hospital
StadGent
Auteur 4
NaamLEROY
InitialenBP
InstituutGhent University Hospital, Ghent University, Centre of Medical Genetics Ghent University Hospital
StadGent
Auteur 5
NaamDE SCHRYVER
InitialenI
InstituutGhent University Hospital
StadGent
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