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Titel

New Therapeutics and Delivery Systems on the Horizon

Doel	Reduction of the intraocular pressure in glaucoma is usually by using eye drops. This delivery method is pulsatile and have multiple limitations. Next to the drug-dependent bioavailability problems, there are various patient- dependent issues, and a true control of the doses of the delivered medication is very difficult. Therefore the real efficacy of the treatment is in each patient different.
Methodes	There is a need for novel delivery systems to address the issue of ocular surface disease, compliance and adherence to ensure consistent reduction of IOP. These delivery systems include contact lenses-releasing glaucoma medications, injectables such as biodegradable micro- and nanoparticles, and surgically implanted systems. These new technologies are aimed at increasing clinical efficacy by offering multiple delivery options and are capable of managing IOP for several months.
Resultaten	Most of these new delivery systems are in research or fase III studies. The long-term results are unkwon.
Conclusie	Interesting session to catch-up with new technoloies in drug delivery.
Belangenverstrengeling	Ja
Details verstrengelde belangen	Consultant for EyeD Pharma

Auteur 1

Naam	POURJAVAN
Initialen	S
Instituut	Chirec Hospitals, site Delta
Stad	Brussels