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TitelInfantile orbital hemangioma treated with propranolol: 2 cases
Abstract Nr.3035
DoelWe report two cases of infantile orbital hemangioma with proptosis, successfully treated with propranolol.
MethodesObservational report of two cases with infantile orbital hemangioma treated with propranolol, including close pediatric and ophthalmological follow-up and imaging.
ResultatenA six week-old girl with a history of premature birth, presented at the pediatric clinic with progressive, unilateral exophthalmos. Ophthalmological evaluation showed normal pupillary reflexes and IOP, with proptosis of the right eye, more pronounced during Valsalva-maneuver. MRI was suggestive for capillary hemangioma. Propranolol was promptly started after cardiological check-up, with a spectacular response seen by day one of treatment.
A 5 month-old boy, born as triplet at 34 weeks postmenstrual age, showed a unilateral proptosis of the right eye, increasing with crying. Furthermore, there were no ophthalmological abnormalities. MRI imaging showed a massive capillary hemangioma in the right orbit. After two weeks of treatment with oral propranolol, the exophthalmos and hemangioma were completely disappeared.
ConclusiePropranolol seems to be a rapidly effective and safe treatment for infantile orbital hemangioma. Nevertheless, administering systemic medication to an infant with a benign condition requires careful multidisciplinary consideration and experienced follow-up, considering the risk of side effects, relapse and resistance to propranolol.
BelangenverstrengelingNee
Auteur 1
NaamDEKLERCK
InitialenEJ
InstituutDpt of Ophthalmology, Ghent University Hospital/AZ Sint-Jan Hospital
StadGhent/Bruges
Auteur 2
NaamVULSTEKE
InitialenC
InstituutDpt of Ophthalmology, AZ Delta Hospital
StadRoeselare
Auteur 3
NaamMATTHIJS
InitialenI
InstituutDpt of Pediatrics, AZ Delta Hospital
StadRoeselare
Auteur 4
NaamDELBEKE
InitialenP
InstituutDpt of Ophthalmology, Ghent University Hospital/AZ Sint-Jan Hospital
StadGhent/Bruges
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