THE BELGIAN OPHTHALMIC ASSOCIATIONS
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| Titel | Low grade T cell primary CNS lymphoma with secondary choroïdal and orbital extension: a case report |
| Abstract Nr. | P018 |
| Doel | A 49-year old female was referred to the Eye Hospital with sudden loss of left visual acuity. She had a 8-year old history of suspected low grade T cell primary CNS lymphoma, though pathology report of the left IVth ventricle roof biopsy at the time did not exclude a granulomatous pseudotumor. Clinical course had been atypical as cerebral lesions had regressed spontaneously and patient had therefore rejected any radio-or chemiotherapeutic proposal so far. Clinical and ultrasonic examination of the left eye showed a non-pigmented choroïdal mass with secondary retinal detachment and orbital extension. Microscopic examination of the orbital biopsy revealed diffuse non-necrotic granulomatous infiltrates with foci of T-lymphocytic aggregation. Only their microdissection and PCR permitted to detect TCR y and TCR y-CDR3 gene rearrangement, finally confirming the exceptional diagnosis of low grade T cell primary CNS lymphoma with secondary choroïdal and orbital extension. |
Auteur 1
| Naam | SCHALENBOURG |
| Initialen | A |
| Stad | Lausanne |
Auteur 2
| Naam | Guex-Crosier |
| Initialen | Y |
| Stad | Lausanne |
Auteur 3
| Naam | Chan |
| Initialen | C |
| Stad | Lausanne |
Auteur 4
| Naam | Zografos |
| Initialen | L |
| Stad | Lausanne |