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Deze abstract is toegekend aan sessie BOG-SBO 1 Medische retina/ Rétine médicale
TitelPhotodynamic treatment of circumscribed choroidal hemangiomas
Abstract Nr.A1009
DoelTo evaluate the safety and efficacy of photodynamic therapy (PDT) in the treatment of symptomatic circumscribed choroidal hemangiomas (CCH).
MethodesThis prospective nonrandomized study included 8 patients referred to us for management of CCH with exudative activity. PDT was applied by diode laser (689nm) with a light dose of 50 J/cm² and using verteporfin (6 mg/m²) IV bolus injection. The treatment spot diameter was related to the tumor basal diameter (TBD).
ResultatenThe mean tumor thickness before PDT was 3.3 mm and the mean largest TBD was 6.9 mm . All patients were managed with a single PDT application. After a mean follow-up of 12 months, all CCH (100%) showed regression of the vascular tumor mass with a final tumor thickness of 2.3 mm and complete resorption of the serous retinal fluid (SRF). All CCH showed overlying PDT–related RPE atrophic changes. No cases of retinal vascular occlusion or recurrent leakage was documented. Six patients (75%) had visual improvement, one (12.5%) had stable vision and one (12.5%) had worse vision due to chronic exudation-related RPE changes.
ConclusiePDT using verteporfin offers a safe and effective option to treat CCH. Complete resorption of the subretinal fluid is associated with visual improvement.
Auteur 1
NaamGUAGNINI
InitialenAP
InstituutOcular Oncology Unit, Cliniques Universitaires St-Luc
StadBrussels
Auteur 2
NaamDE POTTER
InitialenP
InstituutOcular Oncology Unit, Cliniques Universitaires St-Luc
StadBrussels
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