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TitelLong-term results of low-fluence photodynamic therapy in chronic central serous chorioretinopahy
DoelTo evaluate long-term results of low-fluence photodynamic therapy (PDT) with verteporfin in the treatment of Chronic Central Serous Chorioretinopathy (CCSC).
MethodesRetrospective medical record review of 42 eyes (39 patients) who received low-fluence PDT for the treatment of CCSC. Visual acuity, fundus biomicroscopy, fluorescein angiography (FA), indocyanine green angiography (ICG) and optical coherence tomography (OCT) were analysed.
ResultatenForty two eyes (39 patients) with CCSC received low fluence PDT. Mean follow-up after PDT was longer than 3 years (39,43 months; range, 12-96 months; median, 36 months). Mean logMar best corrected visual acuity (BCVA) improved significantly from 0,32 (0,48 Snellen visual acuity) to 0,1 (0,80 Snellen visual acuity) at the last follow up which corresponds to a gain of 2,2 lines in logMar scale. Complete resolution of central subretinal fluid on OCT was achieved 6 months after 1 PDT in 41 eyes and after 2 PDTs in 1 eye (treated at 3 months after first PDT). No treatment-related side effects were observed.
ConclusieLow fluence PDT for CCSC is efficient and safe at long term.
Auteur 1
NaamLEYS
InitialenE
InstituutCHU Brugmann - CHU Saint-Pierre
StadBrussels
Auteur 2
NaamTUTTLE
InitialenS
InstituutCHU Brugmann
StadBrussels
Auteur 3
NaamRASQUIN
InitialenF
InstituutErasme
StadBrussels
Auteur 4
NaamNEU
InitialenF
InstituutErasme
StadBrussels
Auteur 5
NaamPOSTELMANS
InitialenL
InstituutCHU Brugmann
StadBrussels
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