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TitelTreatment of uveal melanoma near to the optic nerve or macula by strontium-90 brachytherapy
Abstract Nr.P007
DoelUveal melanomas localised near to the macula or the optic nerve are difficult to treat by brachytherapy because of the devastating radiation effect on the surrounding tissue. Strontium-90 has a limited penetration depth and very few radiation effects outside the treated area.
MethodesOut of a series of 20 patients, 3 typical clinical cases with uveal melanoma and localisation in the area of the macula or nearer than 3 mm of the optic nerve are presented. All patients were followed for at least 3 years and the visual acuity, visual fields and retinal and choroidal changes are investigated.
ResultatenNo optic nerve atrophy or radiaton retinitis was found after 3 years. All patients could retain good central vision and no loss of vision outside the treated area could be detected.
ConclusieStrontium-90 brachytherapy is favourable for the treatment of difficult uveal melanomas in the vicinity of the macula and the optic nerve without complications in the surrounding tissues
Auteur 1
NaamVAN GINDERDEUREN
InitialenR
InstituutOogziekten UZ Leuven
StadLeuven
Auteur 2
NaamSpileers
InitialenW
InstituutOogziekten UZ Leuven
StadLeuven
Auteur 3
NaamVan Limbergen
InitialenE
Instituutradiotherapie UZ Leuven
StadLeuven
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