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Presentation typeE-poster
TitleContact lens-related Parengyodontium album fungal keratitis: a Case Report
PurposeTo describe the presentation and course of Parengyodontium album fungal keratitis using multimodal imaging.
MethodsCase report of a contact lens-associated fungal keratitis caused by Parengyodontium album, confirmed by culture and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
ResultsA 56-year-old woman, wearing soft monthly contact lenses, presented with a white ring-shaped corneal infiltrate. In vivo confocal microscopy, direct microscopic examination, culture and staining of corneal tissue obtained by scraping showed mycelia. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry confirmed the presence of Parengyodontium album. Although topical antifungal treatment, including voriconazole, amphotericin B and natamycin, stabilized the infection, it failed to achieve complete resolution. Consequently, the patient underwent an adjuvant superficial keratectomy, which resulted in favourable clinical and subjective outcomes.
ConclusionTo our knowledge, no other cases of fungal keratitis caused by Parengyodontium album have been described. To improve early recognition for future patients, this case was thoroughly documented using multimodal imaging. Early diagnosis can allow prompt initiation of antifungal therapy, which may improve clinical outcomes and reduce the need for more invasive surgical interventions.
Conflict of interestNo
Authors 1
Last nameVAN BUYNDER
InitialsC
DepartmentOphthalmology
CityGhent
Authors 2
Last nameRoels
InitialsD
DepartmentOphthalmology
CityGhent
Authors 3
Last nameBoelens
InitialsJ
DepartmentMedical Microbiology and Diagnostic Sciences
CityGhent
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