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Presentation type	E-poster
Title	Evaluation of the iStent Inject® W trabecular micro-bypass stent combined with cataract surgery in cases of controlled chronic open-angle glaucoma – Results at 1 year

Purpose	The iStent Inject® W is a promising addition to the glaucoma therapeutic arsenal. Real-life studies can help delineate its place in current clinical practice. Our purpose is to evaluate the 1-year postoperative efficacy of combined phacoemulsification with iStent inject® W implantation in controlled open-angle glaucoma.
Methods	This is a retrospective, monocentric study. We generated a dataset of 54 eyes from 40 patients with controlled open-angle glaucoma who underwent combined phacoemulsification and iStent inject® W implantation at CHU Liège between January 2023 and May 2025. We included information on preoperative and postoperative intraocular pressure (IOP) up to 15 months of follow-up, and number of glaucoma medications. The primary outcome is the change in IOP, and the secondary outcome is the reduction in the medication burden.
Results	There was a reduction of 20.4% in mean IOP, from a preoperative mean IOP of 16.0 mmHg ± 3.19 mmHg (mean ± standard deviation) to a postoperative IOP of 12.7 ± 2.13 mmHg (p < 0.001). There was a reduction in the mean number of medications in the overall cohort by 54.1%, from 2.02 ± 1.02 preoperatively to 0.93 ± 0.84 postoperatively (p < 0.001). Twenty-five (46.3%) eyes had a reduction of ≥ 20% in IOP. Forty (74.1%) eyes had a reduction of at least 1 medication.
Conclusion	Combined phacoemulsification with iStent inject® W implantation showed a significant reduction in IOP and medication burden in our cohort of 54 eyes at 1-year follow-up.
Conflict of interest	No

Authors 1

Last name	LESOINNE
Initials	P
Department	CHU Liège
City	Liège

Authors 2

Last name	DUPONT
Initials	G
Department	CHU Liège
City	Liège

Authors 3

Last name	GUILLAUME
Initials	S
Department	CHU Liège
City	Liège

Authors 4

Last name	COLLIGNON
Initials	N
Department	CHU Liège
City	Liège