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Title

Evaluation of one-year surgical outcomes of combined pars plana vitrectomy and Paul glaucoma implantation in the vitreous.

Purpose	To evaluate the one-year surgical results and complications of combined pars plana vitrectomy and Paul glaucoma implantation in the vitreous.
Methods	This is a single-center retrospective cohort study. We retrospectively reviewed 29 eyes from 28 patients with uncontrolled glaucoma in a tertiary center. Pre-operative data collected were: baseline IOP and number of medications. Post operative data collected were: IOP recorded at 12 months, clinical and numerical hypotony and the need for further surgical interventions.
Results	There was a reduction of 60.8% in mean IOP in the 29 eyes at 1 year after surgery, from a preoperative mean IOP of 32.4 mmHg (range 18mmHg-50 mmHg) to a postoperative IOP of 12.7 mmHg (range 7-21 mmHg). There was a reduction in the mean number of IOP-lowering medications by 56.6% from an average of 3.0 preoperatively to an average of 1.51 postoperatively. Concerning complications, at 1 year, 2 patients needed further surgeries, and 3 patients experienced hypotony below 6 mmHg during the first few weeks, all resolved spontaneously.
Conclusion	Over the past 10 years, the use of glaucoma drainage devices (GDD) has significantly increased in the management of glaucoma. The Paul glaucoma implant (PGI) is a valveless GDD. For many patients with co-existing retinal pathology or with reduced visibility, performing combined pars plana vitrectomy (PPV) and PGI implantation in the vitreous offers multiple advantages. This retrospective study of 29 eyes showed a surgical success with reduction in IOP and/or reduction in the medication burden. There were no significant complications recorded in our cohort with a relative low level of postoperative hypotony.
Conflict of interest	No

Authors 1

Last name	COLLEE
Initials	C
Department	CHU de Liège
City	Liège

Authors 2

Last name	Van Cauwenberge
Initials	F
Department	CHU de Liège
City	Liège

Authors 3

Last name	Kouam
Initials	C
Department	CHU de Liège
City	Liège

Authors 4

Last name	Rakic
Initials	J-M
Department	CHU de Liège
City	Liège

Authors 5

Last name	Collignon
Initials	N
Department	CHU de Liège
City	Liège