Presentation type | E-poster |
Title | Bilateral infection-triggered ligneous conjunctivitis in a 6-month-old infant treated successfully with heparin and allogenic serum eye drops |
Purpose | To report a case of successful management of ligneous conjunctivitis in a pediatric patient. |
Methods | We present the case of a 6-month-old patient presenting with persistent thick pseudomembranes on the palpebral conjunctiva after an initial episode of infectious conjunctivitis. |
Results | Complete resolution of symptoms was achieved after 5 months of treatment with commercially available heparin eye drops and allogenic serum drops obtained from maternal blood. Genetic testing later revealed a homozygous pathologic variant of the PLG gene confirming diagnosis of ligneous conjunctivitis. |
Conclusion | Ligneous conjunctivitis with ocular pseudomembranes formation is the most common clinical presentation in patients with type I plasminogen deficiency. The fibrin rich pseudomembranes can lead to sight threatening complications and reduce quality of life. This is the first report of full resolution of ocular pseudomembranes after a corticosteroid spearing treatment associating heparin eye drops and allogenic serum eye drops in a pediatric patient. |
Conflict of interest | No |
Initials | CL |
Last name | Comberg |
Department | Department of Ophthalmology CHU Saint-Pierre |
City | Brussels |
Initials | M |
Last name | Kamga |
Department | Department of Ophthalmology CHU Saint-Pierre |
City | Brussels |
Initials | M |
Last name | Masset |
Department | Department of Ophthalmology CHU Saint-Pierre |
City | Brussels |
Initials | M |
Last name | Rachdi |
Department | Department of Ophthalmology CHU Saint-Pierre |
City | Brussels |