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Presentation typeE-poster
TitleBilateral infection-triggered ligneous conjunctivitis in a 6-month-old infant treated successfully with heparin and allogenic serum eye drops
PurposeTo report a case of successful management of ligneous conjunctivitis in a pediatric patient.
MethodsWe present the case of a 6-month-old patient presenting with persistent thick pseudomembranes on the palpebral conjunctiva after an initial episode of infectious conjunctivitis.
ResultsComplete resolution of symptoms was achieved after 5 months of treatment with commercially available heparin eye drops and allogenic serum drops obtained from maternal blood. Genetic testing later revealed a homozygous pathologic variant of the PLG gene confirming diagnosis of ligneous conjunctivitis.
ConclusionLigneous conjunctivitis with ocular pseudomembranes formation is the most common clinical presentation in patients with type I plasminogen deficiency. The fibrin rich pseudomembranes can lead to sight threatening complications and reduce quality of life. This is the first report of full resolution of ocular pseudomembranes after a corticosteroid spearing treatment associating heparin eye drops and allogenic serum eye drops in a pediatric patient.
Conflict of interestNo
Authors 1
InitialsCL
Last nameComberg
DepartmentDepartment of Ophthalmology CHU Saint-Pierre
CityBrussels
Authors 2
InitialsM
Last nameKamga
DepartmentDepartment of Ophthalmology CHU Saint-Pierre
CityBrussels
Authors 3
InitialsM
Last nameMasset
DepartmentDepartment of Ophthalmology CHU Saint-Pierre
CityBrussels
Authors 4
InitialsM
Last nameRachdi
DepartmentDepartment of Ophthalmology CHU Saint-Pierre
CityBrussels
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