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Presentation type	E-poster
Title	Management of epithelial downgrowth after uncomplicated cataract surgery

Methods	Describing the management of 2 cases of epithelial downgrowth (EDG) following cataract surgery.
Results	Both patients were referred with iridocorneal adhesions and corneal decompensation. Patient 1, a 76-year-old woman, had uncorrected visual acuity (UCVA) of 1/10 in the left eye with a history of uneventful phacoemulsification surgery 2 years prior. Patient 2, a 74-year-old man, had an UCVA of 8/10 in the right eye after uncomplicated cataract surgery 8 years prior. Slit lamp examination of both patients showed a fibrotic retrocorneal membrane. Clinical diagnosis of EDG post-cataract surgery was established. Treatment of both patients involved synechiolysis followed by stripping of the epithelial membrane and intracameral injection of 5-FU (500 microgram/0.1mL). Histopathologic examination of the fragments of the excised membrane established the diagnosis of EDG. Patient 1 required UT-DSAEK due to corneal edema and vision loss. Patient 2 had mild corneal edema and epitheliopathy 2 weeks after 5-FU injection, managed with a wait-and-see approach. A UT-DSAEK/DMEK may be necessary if edema persists. In both cases there was no clinical evidence of recurrence of EDG.
Conclusion	Despite modern surgical techniques EDG is sometimes seen as a rare but vision threatening complication after clear cornea cataract surgery. Intracameral 5-FU therapy proves successful as an alternative to aggressive surgical interventions to manage EDG.
Conflict of interest	No

Authors 1

Last name	VANDER EECKEN
Initials	M
Department	Dpt of Ophthalmology, Ghent University Hospital
City	Ghent, Belgium

Authors 2

Last name	VAN DORPE
Initials	J
Department	Dpt of Pathological Anatomy, Ghent University Hospital
City	Ghent, Belgium

Authors 3

Last name	ROELS
Initials	D
Department	Dpt of Ophthalmology, Ghent University Hospital
City	Ghent, Belgium