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Title

Management of aphakic glaucoma following congenital cataract surgery

Purpose	To investigate the clinical findings of patients with aphakic glaucoma after congenital cataract surgery and assess the response to glaucoma treatment.
Methods	After a retrospective chart review, 51 eyes of 18 males and 10 females under 40 who underwent congenital cataract surgery and developed aphakic glaucoma or ocular hypertension were enrolled. Data regarding their glaucoma management was collected and analyzed.
Results	Mean age at the time of cataract surgery was 4.36 ± 4.37 months, with a mean follow-up period of 16.60 ± 10.49 years. Out of the 25 patients who underwent bilateral cataract surgery, 23 developed bilateral glaucoma and mean age at the time of glaucoma diagnosis was 10.88 ± 8.15 years. Medical therapy was effective in 25 eyes (49%), but 26 eyes required surgery. In these 26 eyes, 12 eyes underwent only 1, 6 eyes underwent 2 and 8 eyes underwent 3 or more procedures. Mean age at the time of the first surgical procedure was 13.60 ± 9.40 years. In those eyes under medical treatment only, the mean number of compounds administered was 2.31 ± 0.97. In the 51 eyes included, glaucoma management led to a mean intraocular pressure (IOP) reduction of 45 ± 21%. IOP reduction was significantly correlated with the number of surgical glaucoma procedures performed (p < 0.05).
Conclusion	Aphakic glaucoma following congenital cataract surgery remains difficult to manage, requiring surgery in about half of the patients. Long-term careful follow-up is necessary because of the possibility of late manifestation of aphakic glaucoma.
Conflict of interest	No

Authors 1

Last name	LEMMENS
Initials	S
Department	KU Leuven, UZ Leuven
City	Leuven

Authors 2

Last name	BARBOSA-BREDA
Initials	J
Department	Faculdade de Medicina da Universidade do Porto
City	Porto

Authors 3

Last name	VAN KEER
Initials	K
Department	KU Leuven, UZ Leuven
City	Leuven

Authors 4

Last name	STALMANS
Initials	I
Department	KU Leuven, UZ Leuven
City	Leuven