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TitleRobot assisted retinal vein cannulation in an in vivo porcine retinal vein occlusion model.
Abstract Nr.1053
PurposeTo evaluate the feasibility of robot assisted retinal vein cannulation for retinal vein occlusion.
MethodsProspective experimental study performed in in vivo porcine eyes. A standard three port pars plana vitrectomy was followed by laser induced branch retinal vein occlusion. Consequently, a retinal vein cannulation with the help of a surgical robot and a micro-needle was performed. Complete success was defined as a stable intravenous position of the needle tip confirmed by blood washout for at least 3 minutes. Secondary outcomes were the occurrence of intraoperative complications and technical failures.
ResultsCannulation was successful in 15 out of 18 eyes with a complete success rate (duration of infusion of more than 3 minutes) of 73,3% after exclusion of 2 eyes from analysis due to failure in establishing a blood clot. There were no technical failures regarding the robotic device. The intravessel injections of ocriplasmin in 2 out of 2 eyes led to a clot dissolution. In a subset of 5 eyes, a second cannulation attempt at the border of the optic disc resulted in a stable intravessel position and infusion during 361,8 (±138,45) seconds.
ConclusionRobot assisted retinal vein cannulation with prolonged infusion time is technically feasible. Human experiments are required to analyze the clinical benefit of this new therapy.
Conflict of interestYes
Details of conflicting interestsThrombogenics: grant support
Authors 1
Last nameSTALMANS
InitialsP
DepartmentUZLeuven
Authors 2
Last nameGijbels
InitialsA
DepartmentKULeuven
Authors 3
Last nameSchoevaerdts
InitialsL
DepartmentKULeuven
Authors 4
Last nameEsteveny
InitialsL
DepartmentKULeuven
Authors 5
Last nameReynaerts
InitialsD
DepartmentKULeuven
Authors 6
Last nameVander Poorten
InitialsE
DepartmentKULeuven
Authors 7
Last nameWillekens
InitialsK
DepartmentUZLeuven
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