THE BELGIAN OPHTHALMIC ASSOCIATIONS
View abstract
This abstract is assigned to session Poster session
| Title | Low grade T cell primary CNS lymphoma with secondary choroïdal and orbital extension: a case report |
| Abstract Nr. | P018 |
| Purpose | A 49-year old female was referred to the Eye Hospital with sudden loss of left visual acuity. She had a 8-year old history of suspected low grade T cell primary CNS lymphoma, though pathology report of the left IVth ventricle roof biopsy at the time did not exclude a granulomatous pseudotumor. Clinical course had been atypical as cerebral lesions had regressed spontaneously and patient had therefore rejected any radio-or chemiotherapeutic proposal so far. Clinical and ultrasonic examination of the left eye showed a non-pigmented choroïdal mass with secondary retinal detachment and orbital extension. Microscopic examination of the orbital biopsy revealed diffuse non-necrotic granulomatous infiltrates with foci of T-lymphocytic aggregation. Only their microdissection and PCR permitted to detect TCR y and TCR y-CDR3 gene rearrangement, finally confirming the exceptional diagnosis of low grade T cell primary CNS lymphoma with secondary choroïdal and orbital extension. |
Author 1
| Last name | SCHALENBOURG |
| Initials | A |
| City | Lausanne |
Author 2
| Last name | Guex-Crosier |
| Initials | Y |
| City | Lausanne |
Author 3
| Last name | Chan |
| Initials | C |
| City | Lausanne |
Author 4
| Last name | Zografos |
| Initials | L |
| City | Lausanne |